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1940 |
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1940 |
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G. W. Beadle and E. L. Tatum publish their classic study on the
biochemical genetics of Neurospora and promulgate the ONE-GENE, ONE-ENZYME theory.
K. Mather coins the term polygenes and describes polygenic traits in various organisms.
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1941 |
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S. E. Luria and T. F. Anderson publish the first electron micrographs
of bacterial viruses. T2 has a polyhedral body and a tail.
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1942 |
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S. E. Luria and M. Delbrück initiate the field of bacterial genetics
when they demonstrate unambiguously that bacteria undergo spontaneous mutation.
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1943 |
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O. T. Avery, C. M. MacLeod, and M. McCarty describe the pneumococcus
transforming principle. The fact that it is rich in DNA suggests that DNA and
not protein is the hereditary chemical.
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1944 |
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S. E. Luria demonstrates that mutations occur in bacterial viruses.
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1945 |
FDR dies in office.
Harry S. Truman becomes thirty-third president of the United States.
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J. Lederberg and E. L. Tatum demonstrate genetic recombination in bacteria.
Genetic recombination in bacteriophage is demonstrated by M. Delbrück and W. T. Bailey and by A. D. Hershey. Nobel Prize in Medicine awarded to H. J. Muller for his contributions to radiation genetics |
1946 |
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1947 |
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H. J. Muller coins the term dosage compensation.
J. Lederberg and N. Zinder, and, independently, B. D. Davis develop
the penicillin selection technique for isolating biochemically deficient bacterial mutants.
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1948 |
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A. D. Hershey and R. Rotman demonstrate that genetic recombination occurs in bacteriophage.
J. V. Neel provides genetic evidence that the sickle-cell disease is inherited as a simple
Mendelian autosomal recessive.
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1949 |
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1950 |
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